Wymagania sprzętowe dla Windows:

OS: Windows XP SP3
Processor: 2.4 GHz Dual Core Processor
Memory: 2 GB(XP)/ 2 GB(Vista)
Hard Disk Space: 13 GB free
Video Memory: 256 MB
Video Card: NVIDIA GeForce 8500 /ATI Radeon HD 2600
Sound: DirectX 9.0c Compatible
Other Requirements: Initial installation requires one-time internet connection for Steam authentication.

Wymagania sprzętowe dla Mac:

OS: 10.8.5 (Mountain Lion), 10.9.5 (Mavericks), 10.10.5 (Yosemite), 10.11.6 (El Capitan), 10.12 (Sierra)
Processor: 2.4 GHz Intel Core 2 Duo (Dual-Core)
Memory: 4 GB RAM
Hard Disk Space: 13 GB
Video Memory: 256 MB
Video Card: ATI Radeon HD 2600 / NVidia Geforce 8800/ Intel HD 3000
Additional: Macintosh mouse and keyboard. Borderlands 2 supports both the Xbox 360 wired gamepad AND the PlayStation 3 Dualshock 3 Wireless Controller
Notice:This game is not supported on volumes formatted as Mac OS Extended (Case Sensitive). The following video chipsets are unsupported for Borderlands 2: ATI RADEON HD 2400, NVIDIA 8600m, NVIDIA 9400m, 9600m, Intel Integrated GMA 950, Intel Integrated x3100. The Mac and Linux versions of Borderlands 2 are available in English, French, Italian, German and Spanish only.

Wymagania sprzętowe dla Linux:

OS: SteamOS, Ubuntu 14.04
Processor: Intel Core 2 Quad, AMD Phenom II X4  2.4GHz
Memory: 4 GB RAM
Hard Disk Space: 13 GB
Video Card (NVidia): Geforce 260
Notice: The Mac and Linux versions of Borderlands 2 are available in English, French, Italian, German and Spanish only.