Wymagania sprzętowe dla Windows:

OS: Windows XP SP3/ Windows Vista SP2/ Windows 7
Processor: Intel Core 2 Duo 1.8 GHz or AMD Athlon X2 64 2.0 GHz
Memory: 2GB RAM
Hard Disk Space: 8 GB Free
Video Card: 256 MB ATI HD2600 XT or better, 256 MB nVidia 7900 GS or better, or Core i3 or better integrated graphics
DirectX®: 9.0c
Sound: DirectX 9.0c-compatible sound card

Wymagania sprzętowe dla Mac:

OS: 10.8.5 (Mountain Lion), 10.9.5 (Mavericks), 10.10.5 (Yosemite), 10.11.1 (El Capitan) 
Processor: Intel Core 2 Duo (Dual-Core) CPU Speed: 2.4 GHz 
Memory: 2 GB RAM 
Hard Disk Space: 8 GB 
Video Card: (ATI) Radeon HD 2600, (NVidia) Geforce 8600, (Intel) HD 4000 
Video Memory: 256MB
Multiplayer: Internet (TCP/IP) and LAN (TCP/IP) play supported. Please note, it is possible for Mac and PC to become out of sync during updates. Within this short time period, Mac users will only be able to play other Mac users. 
Notice:This game is not supported on volumes formatted as Mac OS Extended (Case Sensitive) 
Notice: The following video chipsets are not supported for Civilization V: ATI Radeon X1000 series, HD 2400, Nvidia GeForce 7000 series, 8600, 9400, Intel GMA (950/X3100), HD 3000
Notice: The Mac and Linux + SteamOS versions of Sid Meier's Civilization V are available in English, French, Italian, German and Spanish only.

Wymagania sprzętowe dla Linux:

OS: SteamOS, Ubuntu 
Processor: Intel Core i3, AMD A10 2.4GHz 
Memory: 4 GB RAM 
Hard Disk Space: 10 GB 
Video Card: (ATI) Radeon HD 6450, (NVIDIA) Geforce 640M, (INTEL) Iris Pro 
Video Memory: 1GB
Notice: Intel Integrated video chipsets (GMA 9XX, HD 3XXX) will not run Civilization V for SteamOS and Linux, and are unsupported.
Notice: The Mac and Linux + SteamOS versions of Sid Meier's Civilization V are available in English, French, Italian, German and Spanish only.